Edie Campbell grew up in Westbourne Grove, London. Her mother is the architect Sophie Hicks. Her younger sister, Olympia, is also a model, and an actress. She graduated from St. Paul's Girls' School in London. She later graduated from the Courtauld Institute of Art, University of London with a First Class Honours degree in History of Art.
Edie Campbell started modelling after she appeared in a Vogue feature by Mario Testino in a story about up and coming young Londoners. Mario Testino then went on to use her in a Burberry campaign alongside Kate Moss . Campbell is now represented by VIVA Model Management London.
Campbell has appeared in advertising campaigns for Burberry, Cacharel, Christian Dior, Marc Jacobs , Bottega Veneta, Karl Lagerfeld , Lanvin, Alexander McQueen, Hugo Boss , Yves Saint Laurent , Jil Sander and Louis Vuitton . She has walked the runway for prestigious fashion houses such as Burberry, Hermès, Chanel, Christian Dior, Calvin Klein , Balenciaga, Thakoon, Cacharel and Yves Saint Laurent, and has also been featured in fashion stories and cover shoots for publications such as Numero, Love Magazine, British Vogue, Italian Vogue, W and American Vogue. A long-standing favourite of Karl Lagerfeld, Campbell was given what Vogue UK called "one of the ultimate modelling accolades", when she closed the Chanel Spring/Summer 2012 couture show as the "bride".
In the Autumn/Winter 2013 season, Campbell opened the Marc Jacobs, Jil Sander and Louis Vuitton show, whilst also opening and closing the Burberry show. She also featured in the Giles show in London and the Saint Laurent by Hedi Slimane show in Paris. Campbell opened Marc Jacobs' final show for Louis Vuitton in October 2013.
In 2013 Campbell graced the cover of both the April British Vogue and Vogue Italia, as well as the May cover of Vogue Italia, alongside fellow British model Karen Elson . She was one of four covers of LOVE magazine's Autumn/Winter 2013 issue. Campbell starred on the cover of the German Vogue in the same year. In February 2014 Campbell graced four separate covers of Self Service magazine's 20-year special issue, the Spring 2014 cover of i-D magazine and the cover of Vogue Japan.
Campbell was named "Model of the Year" at the prestigious British Fashion Awards in London, December 2013. The award was presented to her by top fashion photographer, Tim Walker , who has collaborated with her on many occasions. In 2013 Campbell also made her journalistic debut, writing a piece for Harpers Bazaar UK. Campbell has also been named as a Contributing Editor for the A/W 2014 issue of Love magazine.
She is an accomplished jockey, and took part in Glorious Goodwood in July 2011, becoming the first winner of the inaugural all ladies charity horse race, The Magnolia Cup, a feat she repeated on See the Storm in 2014. Campbell participated in the celebrated Gucci Masters equestrian event during December 2013.